The Musings of Kindly Old Dr Noyes
The Noyes Lab Rules
- If it sounds like more work, its probably the right thing to do.
- When in doubt, see rule 1.
- Always use a master mix...always.
- Always run a "no insert" ligation control...always.
- Two fold differences are meaningless in biology, except when they aren't.
- Attention to detail is the difference between success and struggle.
- When you try to do everything, you do nothing.
- A little Voodoo never hurts.
- What would Bob Sauer do?
- The Zif268 rule: The best-case scenario is not always the best control.
- Prepare for failure, enjoy success.
- A healthy dose of paranoia is a scientist's best friend.
- Great results start with great reagents.
- Dream big.
Make the night work for you
In biology there is almost always something that can be done at night. Starting a culture, plating some bacteria or yeast, setting up a PCR reaction that runs and holds over night, are just some examples. Making sure the night is working for you is like giving yourself a vacation.
Musings of David Botstein
I remember David saying once at Princeton, "I wish my people would stop working, go home and take a bath or a walk and just think about their work. I think they would improve their research more with that approach than trying to work 24 hours a day."